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AdaptHealth was founded in 2012 as QMES Holdings LLC. The company pursued a consolidation strategy based on acquiring local and regional home-medical-equipment providers and combining administrative, purchasing and billing operations.
In July 2019, AdaptHealth Holdings agreed to combine with DFB Healthcare Acquisitions Corp., a publicly traded special-purpose acquisition company sponsored by Deerfield Management. The transaction was completed on November 8, 2019. The combined company was renamed AdaptHealth Corp. and continued trading on the Nasdaq under the symbol AHCO.
AdaptHealth was added to the S&P SmallCap 600 in August 2022.