| PERCEPTIVE ADVISORS LLC | Director | 863,060Ordinary Shares | — | Buy | |
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| Pepin James Nelson | Gen Counsel and Corp Secretary | 43,800Restricted Stock Units | — | Grant / award | |
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| Pepin James Nelson | Gen Counsel and Corp Secretary | 181,200Stock Option (Right to Buy) | — | Grant / award | |
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| Hothum Mathias | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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| Mason Heather L | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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| Chambre Peter Alan | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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| Forster Eliot | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
|---|
| Carter Paul Rutherford | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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| ATIEH MICHAEL G | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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| REICIN ALISE | Director | 48,000Stock Option (Right to Buy) | — | Grant / award | |
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