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MSA was founded in 1914 after development of the Edison Safety Mining Lamp by mining engineer John T. Ryan Sr. and George H. Deike with help from Thomas Edison following a terrible mine explosion in West Virginia in 1912. The mining lamp was a battery-powered headlamp for miners to help prevent methane -related explosions caused by open flame lamps. Since the turn of the 21st century, MSA has seen record sales. Only a small portion of the company's current products involve mining related products. The company’s competitors include Industrial Scientific Corporation, RAE Systems and Dräger.
In May 2026, MSA announced that it would buy Autronica Fire & Security, which sells fire and gas detection systems, for $555 million from Sentinel Capital Partners.