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SSpyre Therapeutics, Inc.

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Spyre Therapeutics, Inc.

  • Overview
  • Financial statements
  • Metrics
    • Revenue & profit
    • Revenue by segment
    • Launches
    • Revenue concentration
    • Margins
    • Contracted revenue
    • Off-balance-sheet commitments
    • Cash flow
    • Cash & debt
    • Earnings per share
    • P/E ratio
    • Share count & dilution
  • Quarterly earnings
  • Burn Rate
  • Similar companies
  • Insider Transactions
Loading financial graphs

Metrics

Revenue & profit
Revenue by segment
Margins
Contracted revenue
Cash flow
Cash & debt
Earnings per share
Share count & dilution

Metrics

Compare sales with the profit left after direct costs and the profit left after all expenses and taxes.Formula: Gross profit = revenue − cost of revenue Net income = total income − total expenses
Q4 ’24201720182019202020212022202320242026-200M-150M-100M-50M0Latest period Q4 '24. Revenue 0. Gross profit 0. Net profit -56.3M.
RevenueGross profitNet profit
See which business lines, products, or regions generate the company’s sales.Formula: Company revenue = Σ(segment revenues) + reconciliation adjustments
Q4 ’2420172018201920202021202220232024202602M4M6M8M10M12M
Development FeeLicense
See how much of each dollar of sales remains after direct costs, after running the business, and after all expenses and taxes.Formula: Gross margin = gross profit ÷ revenue × 100% Operating margin = operating income ÷ revenue × 100% Net margin = net income ÷ revenue × 100%
Q4 ’24201720182019202020212022202320242026-30,000%-20,000%-10,000%0%Latest period Q4 '24. No revenue — margins undefined.
Gross marginOperating marginNet profit marginNo revenue (margins undefined)
Compare cash generated by the business, spending on long-lived assets, and what remains afterward.Formula: Free cash flow = operating cash flow − capital expenditures
$
Q2 ’26201720182019202020212022202320242025-60M-40M-20M0
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    Latest period Q2 '26. Operating cash flow -69.9M.
    Operating cash flowCapexFree cash flow
    Compare the company’s cash cushion with its borrowings. Negative net cash means debt is greater than cash.Formula: Net cash = cash − debt
    2026201720182019202020212022202320242025050M100M150M200M
        Latest period 2026. Cash 162M.
        CashDebtNet cash
        Profit for each share over the trailing 12 months, adjusted for stock splits.Formula: Earnings available to common shareholders ÷ weighted-average shares
        $/shareUsing split history cached 2026-09-23; assuming no new splits
        Q2 ’26201720182019202020212022202320242025-800.00-600.00-400.00-200.000.00
          • Earnings period 2017-01-01 to 2017-03-31. Shares as of 2017-03-31: 13,452,260 source shares.
          • Earnings period 2017-04-01 to 2017-06-30. Shares as of 2017-06-30: 16,452,260 source shares.
          • Earnings period 2017-07-01 to 2017-09-30. Shares as of 2017-09-30: 16,472,831 source shares.
          • Earnings period 2017-01-01 to 2017-12-31. Shares as of 2017-12-31: 16,670,188 source shares.
          • Earnings period 2018-01-01 to 2018-03-31. Shares as of 2018-03-31: 16,809,669 source shares.
          • Earnings period 2018-04-01 to 2018-06-30. Shares as of 2018-06-30: 21,908,192 source shares.
          • Earnings period 2018-07-01 to 2018-09-30. Shares as of 2018-09-30: 22,098,218 source shares.
          • Earnings period 2018-01-01 to 2018-12-31. Shares as of 2018-12-31: 24,140,097 source shares.
          • Earnings period 2019-01-01 to 2019-03-31. Shares as of 2019-03-31: 28,837,352 source shares.
          • Earnings period 2019-04-01 to 2019-06-30. Shares as of 2019-06-30: 28,848,303 source shares.
          • Earnings period 2019-07-01 to 2019-09-30. Shares as of 2019-09-30: 28,923,241 source shares.
          • Earnings period 2019-01-01 to 2019-12-31. Shares as of 2019-12-31: 29,084,437 source shares.
          • Earnings period 2020-01-01 to 2020-03-31. Shares as of 2020-03-31: 29,147,461 source shares.
          • Earnings period 2020-04-01 to 2020-06-30. Shares as of 2020-08-05: 44,599,847 source shares. Uses later-dated shares from the same quarterly filing.
          • Earnings period 2020-07-01 to 2020-09-30. Shares as of 2020-09-30: 44,692,030 source shares.
          • Earnings period 2020-01-01 to 2020-12-31. Shares as of 2020-12-31: 47,959,086 source shares.
          • Earnings period 2021-01-01 to 2021-03-31. Shares as of 2021-03-31: 49,019,901 source shares.
          • Earnings period 2021-04-01 to 2021-06-30. Shares as of 2021-06-30: 49,025,956 source shares.
          • Earnings period 2021-07-01 to 2021-09-30. Shares as of 2021-09-30: 49,306,107 source shares.
          • Earnings period 2021-01-01 to 2021-12-31. Shares as of 2021-12-31: 49,355,130 source shares.
          • Earnings period 2022-01-01 to 2022-03-31. Shares as of 2022-03-31: 49,419,873 source shares.
          • Earnings period 2022-04-01 to 2022-06-30. Shares as of 2022-06-30: 61,172,510 source shares.
          • Earnings period 2022-07-01 to 2022-09-30. Shares as of 2022-09-30: 61,511,078 source shares.
          • Earnings period 2022-01-01 to 2022-12-31. Shares as of 2022-12-31: 2,614,014 source shares.
          • Earnings period 2023-01-01 to 2023-03-31. Shares as of 2023-03-31: 65,395,159 source shares.
          • Earnings period 2023-04-01 to 2023-06-30. Shares as of 2023-06-30: 81,001,676 source shares.
          • Earnings period 2023-07-01 to 2023-09-30. Shares as of 2023-09-30: 4,048,687 source shares.
          • Earnings period 2023-01-01 to 2023-12-31. Shares as of 2023-12-31: 36,057,109 source shares.
          • Earnings period 2024-01-01 to 2024-03-31. Shares as of 2024-03-31: 36,629,680 source shares.
          • Earnings period 2024-04-01 to 2024-06-30. Shares as of 2024-06-30: 50,783,384 source shares.
          • Earnings period 2024-07-01 to 2024-09-30. Shares as of 2024-09-30: 51,395,608 source shares.
          • Earnings period 2024-01-01 to 2024-12-31. Shares as of 2024-12-31: 60,257,023 source shares.
          • Earnings period 2025-01-01 to 2025-03-31. Shares as of 2025-03-31: 60,275,561 source shares.
          • Earnings period 2025-04-01 to 2025-06-30. Shares as of 2025-06-30: 60,372,927 source shares.
          • Earnings period 2025-07-01 to 2025-09-30. Shares as of 2025-09-30: 60,471,793 source shares.
          • Earnings period 2025-01-01 to 2025-12-31. Shares as of 2025-12-31: 78,189,811 source shares.
          • Earnings period 2026-01-01 to 2026-03-31. Shares as of 2026-03-31: 78,839,858 source shares.
          • Earnings period 2026-04-01 to 2026-06-30. Shares as of 2026-06-30: 88,064,133 source shares.
          Latest period Q2 2026. EPS (TTM) -2.03.
          EPS (TTM)
          How much investors pay for each dollar of the company’s yearly earnings. It is not useful when the company has no profit.Formula: Share price ÷ trailing 12-month EPS
          Using split history cached 2026-09-23; assuming no new splits
          Security type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingQ2 ’262017201820192020202120222023202420250x0.2x0.4x0.6x0.8x1x
          • Q1 2017: Security type not verified
          • Q2 2017: Security type not verified
          • Q3 2017: Security type not verified
          • FY 2017: Security type not verified
          • Q1 2018: Security type not verified
          • Q2 2018: Security type not verified
          • Q3 2018: Security type not verified
          • FY 2018: Security type not verified
          • Q1 2019: Security type not verified
          • Q2 2019: Security type not verified
          • Q3 2019: Security type not verified
          • FY 2019: Security type not verified
          • Q1 2020: Security type not verified
          • Q2 2020: Security type not verified
          • Q3 2020: Security type not verified
          • FY 2020: Security type not verified
          • Q1 2021: Security type not verified
          • Q2 2021: Security type not verified
          • Q3 2021: Security type not verified
          • FY 2021: Security type not verified
          • Q1 2022: Security type not verified
          • Q2 2022: Security type not verified
          • Q3 2022: Security type not verified
          • FY 2022: Security type not verified
          • Q1 2023: Security type not verified
          • Q2 2023: Security type not verified
          • Q3 2023: Security type not verified
          • FY 2023: Security type not verified
          • Q1 2024: Security type not verified
          • Q2 2024: Security type not verified
          • Q3 2024: Security type not verified
          • FY 2024: Security type not verified
          • Q1 2025: Security type not verified
          • Q2 2025: Security type not verified
          • Q3 2025: Security type not verified
          • FY 2025: Security type not verified
          • Q1 2026: Security type not verified
          • Q2 2026: Security type not verified
          • Earnings period 2017-01-01 to 2017-03-31. Shares as of 2017-03-31: 13,452,260 source shares.
          • Earnings period 2017-04-01 to 2017-06-30. Shares as of 2017-06-30: 16,452,260 source shares.
          • Earnings period 2017-07-01 to 2017-09-30. Shares as of 2017-09-30: 16,472,831 source shares.
          • Earnings period 2017-01-01 to 2017-12-31. Shares as of 2017-12-31: 16,670,188 source shares.
          • Earnings period 2018-01-01 to 2018-03-31. Shares as of 2018-03-31: 16,809,669 source shares.
          • Earnings period 2018-04-01 to 2018-06-30. Shares as of 2018-06-30: 21,908,192 source shares.
          • Earnings period 2018-07-01 to 2018-09-30. Shares as of 2018-09-30: 22,098,218 source shares.
          • Earnings period 2018-01-01 to 2018-12-31. Shares as of 2018-12-31: 24,140,097 source shares.
          • Earnings period 2019-01-01 to 2019-03-31. Shares as of 2019-03-31: 28,837,352 source shares.
          • Earnings period 2019-04-01 to 2019-06-30. Shares as of 2019-06-30: 28,848,303 source shares.
          • Earnings period 2019-07-01 to 2019-09-30. Shares as of 2019-09-30: 28,923,241 source shares.
          • Earnings period 2019-01-01 to 2019-12-31. Shares as of 2019-12-31: 29,084,437 source shares.
          • Earnings period 2020-01-01 to 2020-03-31. Shares as of 2020-03-31: 29,147,461 source shares.
          • Earnings period 2020-04-01 to 2020-06-30. Shares as of 2020-08-05: 44,599,847 source shares. Uses later-dated shares from the same quarterly filing.
          • Earnings period 2020-07-01 to 2020-09-30. Shares as of 2020-09-30: 44,692,030 source shares.
          • Earnings period 2020-01-01 to 2020-12-31. Shares as of 2020-12-31: 47,959,086 source shares.
          • Earnings period 2021-01-01 to 2021-03-31. Shares as of 2021-03-31: 49,019,901 source shares.
          • Earnings period 2021-04-01 to 2021-06-30. Shares as of 2021-06-30: 49,025,956 source shares.
          • Earnings period 2021-07-01 to 2021-09-30. Shares as of 2021-09-30: 49,306,107 source shares.
          • Earnings period 2021-01-01 to 2021-12-31. Shares as of 2021-12-31: 49,355,130 source shares.
          • Earnings period 2022-01-01 to 2022-03-31. Shares as of 2022-03-31: 49,419,873 source shares.
          • Earnings period 2022-04-01 to 2022-06-30. Shares as of 2022-06-30: 61,172,510 source shares.
          • Earnings period 2022-07-01 to 2022-09-30. Shares as of 2022-09-30: 61,511,078 source shares.
          • Earnings period 2022-01-01 to 2022-12-31. Shares as of 2022-12-31: 2,614,014 source shares.
          • Earnings period 2023-01-01 to 2023-03-31. Shares as of 2023-03-31: 65,395,159 source shares.
          • Earnings period 2023-04-01 to 2023-06-30. Shares as of 2023-06-30: 81,001,676 source shares.
          • Earnings period 2023-07-01 to 2023-09-30. Shares as of 2023-09-30: 4,048,687 source shares.
          • Earnings period 2023-01-01 to 2023-12-31. Shares as of 2023-12-31: 36,057,109 source shares.
          • Earnings period 2024-01-01 to 2024-03-31. Shares as of 2024-03-31: 36,629,680 source shares.
          • Earnings period 2024-04-01 to 2024-06-30. Shares as of 2024-06-30: 50,783,384 source shares.
          • Earnings period 2024-07-01 to 2024-09-30. Shares as of 2024-09-30: 51,395,608 source shares.
          • Earnings period 2024-01-01 to 2024-12-31. Shares as of 2024-12-31: 60,257,023 source shares.
          • Earnings period 2025-01-01 to 2025-03-31. Shares as of 2025-03-31: 60,275,561 source shares.
          • Earnings period 2025-04-01 to 2025-06-30. Shares as of 2025-06-30: 60,372,927 source shares.
          • Earnings period 2025-07-01 to 2025-09-30. Shares as of 2025-09-30: 60,471,793 source shares.
          • Earnings period 2025-01-01 to 2025-12-31. Shares as of 2025-12-31: 78,189,811 source shares.
          • Earnings period 2026-01-01 to 2026-03-31. Shares as of 2026-03-31: 78,839,858 source shares.
          • Earnings period 2026-04-01 to 2026-06-30. Shares as of 2026-06-30: 88,064,133 source shares.
          Latest period Q2 2026. P/E ratio Missing.
          P/E ratio
          See how the number of shares changes over time. More shares can mean each existing share owns a smaller slice of the company.Formula: Outstanding shares = issued shares − treasury shares Share-count growth = (current shares ÷ previous shares − 1) × 100%
          Stock split history may be out of date.
          2026201720182019202020212022202320242025020M40M60M80M
          2023-09-08: Reverse stock split 1-for-25
              Latest period 2026. Shares outstanding 88.1M. Class detail unavailable 88.1M.
              Class detail unavailableStock split