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UUpstream Bio, Inc.

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Upstream Bio, Inc.

  • Overview
  • Financial statements
  • Metrics
    • Revenue & profit
    • Revenue by segment
    • Launches
    • Revenue concentration
    • Margins
    • Contracted revenue
    • Off-balance-sheet commitments
    • Cash flow
    • Cash & debt
    • Earnings per share
    • P/E ratio
    • Share count & dilution
  • Quarterly earnings
  • Burn Rate
  • Similar companies
  • Insider Transactions
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Metrics

Revenue & profit
Revenue by segment
Margins
Contracted revenue
Cash flow
Cash & debt
Earnings per share
Share count & dilution

Metrics

Compare sales with the profit left after direct costs and the profit left after all expenses and taxes.Formula: Gross profit = revenue − cost of revenue Net income = total income − total expenses
Q2 ’262023202420252026-40M-30M-20M-10M0Latest period Q2 '26. Revenue 773K. Gross profit 773K. Net profit -39.7M.
RevenueGross profitNet profit
See how much of each dollar of sales remains after direct costs, after running the business, and after all expenses and taxes.Formula: Gross margin = gross profit ÷ revenue × 100% Operating margin = operating income ÷ revenue × 100% Net margin = net income ÷ revenue × 100%
Q2 ’262023202420252026-6,000%-4,000%-2,000%0%Latest period Q2 '26. Gross margin 100%. Operating margin -5,481%. Net profit margin -5,136.1%.
Gross marginOperating marginNet profit margin
Compare cash generated by the business, spending on long-lived assets, and what remains afterward.Formula: Free cash flow = operating cash flow − capital expenditures
$
Q2 ’262023202420252026-40M-30M-20M-10M0
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    • Capex: purchases of property, plant and equipment
    Latest period Q2 '26. Operating cash flow -35.6M.
    Operating cash flowCapexFree cash flow
    Compare the company’s cash cushion with its borrowings. Negative net cash means debt is greater than cash.Formula: Net cash = cash − debt
    202620232024202520260100M200M300M
        Latest period 2026. Cash 79.4M. Debt 0.
        CashDebtNet cash
        Profit for each share over the trailing 12 months, adjusted for stock splits.Formula: Earnings available to common shareholders ÷ weighted-average shares
        $/shareUsing split history cached 2026-09-23; assuming no new splits
        four_consecutive_quarters_unavailableMissingfour_consecutive_quarters_unavailableMissingQ2 ’262023202420252026-20.00-15.00-10.00-5.000.00
        • Q3 2023: four consecutive quarters unavailable
        • Q1 2024: four consecutive quarters unavailable
        • Earnings period 2023-07-01 to 2023-09-30. Shares as of 2023-09-30: unavailable source shares.
        • Earnings period 2023-01-01 to 2023-12-31. Shares as of 2023-12-31: 2,992,479 source shares.
        • Earnings period 2024-01-01 to 2024-03-31. Shares as of 2024-03-31: unavailable source shares.
        • Earnings period 2024-04-01 to 2024-06-30. Shares as of 2025-08-04: 53,909,427 source shares. Uses later-dated shares from the same quarterly filing.
        • Earnings period 2024-07-01 to 2024-09-30. Shares as of 2024-09-30: 3,025,452 source shares.
        • Earnings period 2024-01-01 to 2024-12-31. Shares as of 2024-12-31: 53,603,398 source shares.
        • Earnings period 2025-01-01 to 2025-03-31. Shares as of 2025-03-31: 53,640,895 source shares.
        • Earnings period 2025-04-01 to 2025-06-30. Shares as of 2025-06-30: 53,798,151 source shares.
        • Earnings period 2025-07-01 to 2025-09-30. Shares as of 2025-09-30: 53,999,522 source shares.
        • Earnings period 2025-01-01 to 2025-12-31. Shares as of 2025-12-31: 54,237,750 source shares.
        • Earnings period 2026-01-01 to 2026-03-31. Shares as of 2026-03-31: 54,419,986 source shares.
        • Earnings period 2026-04-01 to 2026-06-30. Shares as of 2026-06-30: 54,771,041 source shares.
        Latest period Q2 2026. EPS (TTM) -2.86.
        EPS (TTM)
        How much investors pay for each dollar of the company’s yearly earnings. It is not useful when the company has no profit.Formula: Share price ÷ trailing 12-month EPS
        Using split history cached 2026-09-23; assuming no new splits
        Security type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingSecurity type not verifiedMissingQ2 ’2620232024202520260x0.2x0.4x0.6x0.8x1x
        • Q3 2023: Security type not verified
        • FY 2023: Security type not verified
        • Q1 2024: Security type not verified
        • Q2 2024: Security type not verified
        • Q3 2024: Security type not verified
        • FY 2024: Security type not verified
        • Q1 2025: Security type not verified
        • Q2 2025: Security type not verified
        • Q3 2025: Security type not verified
        • FY 2025: Security type not verified
        • Q1 2026: Security type not verified
        • Q2 2026: Security type not verified
        • Earnings period 2023-07-01 to 2023-09-30. Shares as of 2023-09-30: unavailable source shares.
        • Earnings period 2023-01-01 to 2023-12-31. Shares as of 2023-12-31: 2,992,479 source shares.
        • Earnings period 2024-01-01 to 2024-03-31. Shares as of 2024-03-31: unavailable source shares.
        • Earnings period 2024-04-01 to 2024-06-30. Shares as of 2025-08-04: 53,909,427 source shares. Uses later-dated shares from the same quarterly filing.
        • Earnings period 2024-07-01 to 2024-09-30. Shares as of 2024-09-30: 3,025,452 source shares.
        • Earnings period 2024-01-01 to 2024-12-31. Shares as of 2024-12-31: 53,603,398 source shares.
        • Earnings period 2025-01-01 to 2025-03-31. Shares as of 2025-03-31: 53,640,895 source shares.
        • Earnings period 2025-04-01 to 2025-06-30. Shares as of 2025-06-30: 53,798,151 source shares.
        • Earnings period 2025-07-01 to 2025-09-30. Shares as of 2025-09-30: 53,999,522 source shares.
        • Earnings period 2025-01-01 to 2025-12-31. Shares as of 2025-12-31: 54,237,750 source shares.
        • Earnings period 2026-01-01 to 2026-03-31. Shares as of 2026-03-31: 54,419,986 source shares.
        • Earnings period 2026-04-01 to 2026-06-30. Shares as of 2026-06-30: 54,771,041 source shares.
        Latest period Q2 2026. P/E ratio Missing.
        P/E ratio
        See how the number of shares changes over time. More shares can mean each existing share owns a smaller slice of the company.Formula: Outstanding shares = issued shares − treasury shares Share-count growth = (current shares ÷ previous shares − 1) × 100%
        Stock split history may be out of date.
        20262023202420252026010M20M30M40M50M
            Latest period 2026. Shares outstanding 54.8M. Class detail unavailable 54.8M.
            Class detail unavailable