| Leite John | Global Chief Commercial Off | 4,015Common Stock | — | Sell | |
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| Holstein Jens | Director | 5,000Common Stock | — | Sell | |
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| Febbo Phillip G. | Chief Scientific & Med Officer | 13,110Common Stock | — | Sell | |
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| Chambers Rebecca | Chief Financial Officer | 3,652Common Stock | — | Sell | |
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| McGuire Annie | EVP, General Counsel | 3,254Common Stock | — | Sell | |
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| Stapley Marc | Chief Executive Officer | 8,782Common Stock | — | Tax withholding | |
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| Wygant Jonathan | VP, Chief Accounting Officer | 1,361Common Stock | — | Tax withholding | |
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| Febbo Phillip G. | Chief Scientific & Med Officer | 3,639Common Stock | — | Tax withholding | |
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| Chambers Rebecca | Chief Financial Officer | 3,603Common Stock | — | Tax withholding | |
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| McGuire Annie | EVP, General Counsel | 3,215Common Stock | — | Tax withholding | |
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